Research as a Master of Science Student
- Iowa State University, Ames, Iowa
Contribution to research of cholesterol metabolism and proper nutrition,i.e., cholesterol reduction methods in food.
Research as a Pre-Doctoral Student
- Washington State University, Pullman, Washington
Contribution to fundamental understanding of an enzyme (Isocitrate Lyase) function led to potential therapeutic options for bacterial and parasitic infections.
Research as a Post-Doctoral Fellow
- Johns Hopkins University, Baltimore, Maryland
- Contribution to molecular understanding of the genetic disease, Cystic Fibrosis and potential therapeutics for protein mis-folding diseases.
- Contribution to mitochondrial membrane protein bioenergetics: Discovery and purification of a membrane protein called “ATP Synthasome” from mammalian mitochondria. This is the enzyme that provides the energy necessary to fuel numerous metabolic and physiological processes and is an important target for cancer therapy.
Research as an Assistant Professor
- Johns Hopkins University, Baltimore, Maryland
Discovery of a small molecule, called 3-bromopyruvate (3BP) as a potent and selective anticancer agent.
Independent Research and Global Collaborations
- Germany, Belgium, Poland, Portugal, the Netherlands, and Korea
Translational research by taking a bench side discovery to bedside therapy. Proof of principle was met for 3BP as an effective anticancer agent. In addition, other independent research includes investigating some metabolites, proteins/peptides, and compounds from natural sources for treating other dysfunctional conditions.