Real World Case 1 – 16 Y/O Male

A Translational Study 'Case Report' on the Small Molecule 'Energy Blocker' 3-Bromopyruvate (3BP) as a Potent Anticancer Agent: From Bench Side to Bedside(2012)
The first patient to be treated with Dr. Ko's 3BP compound.


  • Treated at Frankfurt University in 2009
  • 16yr old patient with progressive fibrolamellar hepatocellular carcinoma, 3 month of prognosis
  • The patient was given 9 doses of KAT (200 mg) over a period of 6 months
  • After treatment, the patient loses cancer and the tissue regenerates from 5% to 30%
  • 1.5years after CR, the patient dies of pneumonia due to excessive antibiotic therapy that destroyed liver function. No cancer was found as a result of CT scan by postmortem examination


  • Left images taken before treatment, right images taken after 9th treatment.
  • Tumors throughout liver (L) are necrotic, encapsulated, and showing fibrosis.
  • Lymph nodes that were enlarged (green star) have returned to stable size and shape.
  • Spleen size (S) that was enlarged has drastically reduced.

Real World Case 2 – 70 Y/O Male w/ Melanoma

In 2017, 70 y/o male had biopsy taken of forehead growth.


  • While waiting for the results, the patient starts applying wet gauze to the wound with KAT
  • A biopsy revealed the melanoma and a surgery was scheduled. The melanoma disappears as wound area heals
  • Observation of patients for one year without proof of recurrence


3BP completely remissed the remaining Melanoma after initial biopsy

Real World Case 3 – 100 Y/O Male


  • He was diagnosed with bladder cancer in February 2018, and biopsy showed high levels of aggressive urethra epithelial cell carcinoma.
  • PET tests before treatment showed three cancers in the bladder and one in the lung.
  • After bladder KAT therapy wash, the bladder was cleaned. Also found three cancers in the lung which were diagnosed in PET scan.
    (Note: It is common for KAT to discover other tumors that have not yet been identified in PET imaging.)
  • After IV and in-mouth KAT treatment, bladder wash was also performed, and the third PET scan showed only one cancer in the lung area and the mass was smaller.
  • Now he is doing well and using ketone-producing diets with supplements.


  • April 2018 : A urologist eventually removed a tumor that was found, but only to the extent that surgery was possible.
    Biopsy revealed advanced aggressive epithelial cancer.
  • May 2018 : Patient began a KAT bladder washing treatment applied through a catheter.
  • June 2018 (A) : PET scan showed no lesions in bladder but 3 lesions in lung.
  • July 2018 : Intravenous and oral KAT therapy were added. The bladder wash continued on most alternate days, without intravenous treatment.
  • Sep. 2018 (B) : PET scan showed small spots in the lungs.
    There was no cancer in the bladder

Real World Case 4 – Mid-50s Y/O Female


  • A patient suffers from Stage IV neuroendocrine cancer has been receiving intermittent KAT treatment for the past decade.
  • Genetic reasons have caused her tumor to reappear several times, but the KAT was able to control it effectively without side effects.
  • The patient still lives a normal life. (Bottom Right, 20th Oct. 2018)



The patient still lives a normal life.

Candidates of Initial Indication